33 research outputs found

    Determination of the suitable drilling operating parameters in different geological formations El-Sharara Oil Field (South-Western Libya)

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    Purpose. The objective of this study is to determine the best operating conditions for the most notable drilling parameters (i.e. weight on bit (WOB), rotary drilling speed (RPM), and characteristics of drilling fluid) using field data obtained from El-Sharara Oil Field. Methods. The used data has been extracted from daily drilling reports of well named (NC-186/K04h) field. Such data contains information about the geological formations, casing strings, drill-bits, fuel consumption, flow rate of drilling fluid and other drilling parameters. Findings. The results reveal that, the lower geological formations of El-Sharara Oil Field, the harder are the upper formations. Therefore, it is recommended to apply heavy loads (i.e. WOB of 45000 lb) with low drilling speed (i.e. 100 rpm) in the lower formations; and to apply small loads (i.e. WOB of 19000 lb) with high drilling speed (i.e. 160 rpm) in the upper formations. Originality. This study evaluates the performance of drilling operation based on the interaction between rock formations and machine drilling parameters. Practical implications. Understanding such interaction between rock formations and machine drilling parameters will remarkably improve the rate of penetration (ROP) in the related geological formations. Consequently, the overall drilling costs will be reduced in terms of drilling time, life of drill-bit and fuel consumption.Мета. Визначення оптимальних експлуатаційних умов для технологічних параметрів буріння – осьового навантаження на долото (ОНД), швидкості обертального буріння (ШOБ), характеристик бурового розчину на основі емпіричних даних, отриманих на нафтовому родовищі Ель-Шарара. Методика. У роботі вивчені та систематизовані дані експлуатації нафтової свердловини NC-186/K04h, що містять інформацію про геологічні формації родовища, обсадних колонах, бурових коронках, витрат палива і бурової рідини та інших параметрах буріння. Результати. Дослідження показало, що, чим нижче розташовані нафтоносні геологічні формації Ель-Шарара, тим міцніше породи верхніх формацій. Рекомендовано застосовувати велике навантаження (ОНД – близько 104 кг), при низькій ШOБ (100 об/хв) у нижніх формаціях; і мале навантаження (ОНД – 86 кг) при високій ШOБ (160 об/хв) – у верхніх формаціях. Встановлено кореляційний взаємозв’язок комплексу технологічних параметрів буріння з умовами геологічних формацій родовища. Наукова новизна. Для умов нафтового родовища Ель-Шарара дана наукова оцінка ефективності буріння на основі встановлення взаємозв’язку параметрів формацій і бурових установок. Практична значимість. Врахування взаємозв’язку геологічних формацій і параметрів механічного буріння дозволить суттєво підвищити швидкість проходки свердловин, при цьому загальні витрати на буріння будуть скорочені за рахунок зменшення часу буріння, споживання палива та збільшення терміну служби бурових коронок.Цель. Определение оптимальных эксплуатационных условий для технологических параметров бурения – осевой нагрузки на долото (ОНД), скорости вращательного бурения (СВБ), характеристик бурового раствора на основе эмпирических данных, полученных на нефтяном месторождении Эль-Шарара. Методика. В работе изучены и систематизированы данные о эксплуатации нефтяной скважины NC-186/K04h, которые содержат информацию о геологических формациях месторождения, обсадных колоннах, буровых коронках, расходе топлива и буровой жидкости, а также других параметрах бурения. Результаты. Исследование показало, что, чем ниже расположены нефтеносные геологические формации Эль-Шарара, тем тверже породы верхних формаций. Рекомендуется применять большую нагрузку (ОНД – около 104 кг), при низкой СВБ (100 вр/мин) в нижних формациях; и малую нагрузку (ОНД – 86 кг) при высокой СВБ (160 вр/мин) – в верхних формациях. Установлена корреляционная взаимосвязь комплекса технологических параметров бурения с условиями геологических формаций месторождения. Научная новизна. Для условий нефтяного месторождения Эль-Шарара дана научная оценка эффективности бурения на основе установления взаимосвязи параметров формаций и буровых установок. Практическая значимость. Учет взаимосвязи геологических формаций и параметров механического бурения позволит существенно увеличить скорость проходки скважин, при этом общие затраты на бурение будут сокращены за счет уменьшения времени бурения, потребления топлива и увеличения срока службы буровых коронок.The authors declare that the paper has not been originated under any project and no funding has been raised for this research

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Association of MALAT1 and PVT1 Variants, Expression Profiles and Target miRNA-101 and miRNA-186 with Colorectal Cancer: Correlation with Epithelial-Mesenchymal Transition

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    The influence of PVT1 and MALAT1 variants on colorectal cancer (CRC) susceptibility and their impact on PVT1/miRNA-186/epithelial-mesenchymal transition (EMT) and MALAT1/miRNA-101/EMT axes in CRC are unknown. We investigated the influence of PVT1 rs13255292 and MALAT1 rs3200401 on the risk of CRC and adenomatous polyps (AP), their impact on the long noncoding RNAs PVT1 and MALAT1 expression and their target miRNA-186, miRNA-101/E-cadherin pathways, along with their potential as early CRC biomarkers. Overall, 280 individuals were recruited: 140 patients with CRC, 40 patients with AP, and 100 healthy volunteers. Genotyping and serum expression profiles were assessed using qPCR. The EMT biomarker, E-cadherin, was measured by ELISA. rs3200401 was associated with increased CRC risk, whereas rs13255292 was protective. Serum PVT1 and MALAT1 were upregulated in CRC and AP patients versus healthy controls, whereas, miRNA-186, miRNA-101 and E-cadherin were downregulated in CRC versus non-CRC groups. MALAT1 showed superior diagnostic potential for CRC and predicted CRC risk among non-CRC groups in the multivariate logistic analysis. PVT1, MALAT1, miRNA-186 and miRNA-101 levels were correlated with E-cadherin, tumor stage, lymph node and distant metastasis. E-cadherin was lost in metastatic vs. non-metastatic CRC. rs3200401CC genotype carriers showed higher E-cadherin levels than CC + CT carriers. rs3200401 was correlated with lymph node status. For the first time, rs13255292 and rs3200401 are potential genetic CRC predisposition markers, with rs3200401 possibly impacting the EMT process. Serum PVT1, MALAT1, miRNA-186 and miRNA-101 are novel non-invasive diagnostic biomarkers that could improve the clinical outcome of CRC

    Softening of sub-continental lithosphere prior rifting: Evidence from clinopyroxene chemistry in peridotite xenoliths from Natash volcanic province, SE Egypt

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    International audienceMajor and trace element compositions were determined for well-preserved diopside relics in highly altered mantle xenoliths from Natash volcanic province, south Eastern Desert of Egypt, to unravel the major magmatic processes that occurred within the lithospheric mantle long time before the Red Sea rift. The diopside shows a limited compositional range as for mg# (0.89–0.92), Al2O3 (3.52–5.60 wt%), andTiO2 (0.15–0.35 wt%), whereas it is characterised by a larger variability as for Na2O (0.23–1.83 wt%) and, in particular the trace elements. The latter identify two main diopside types: 1) CPX-I has low abundances of incompatible elements, spoon-like REE patterns, small negative anomalies in Ti and Zr and a positive anomaly in Sr; and 2) CPX-II has high abundances in incompatible elements, REE patterns with steady enrichment from HREE to LREE patterns and marked negative anomalies in Ti and Zr. The range of REE patterns in the mantle section can be explained by 7–22% batch melting of the primitive mantle followed by varying degrees of trace element chromatographic exchange. CPX-I underwent only small-scale reactive porous flow metasomatism at the percolation front, whereas CPX-II resulted from large-scale rock–melt interaction close to the melt source. Trace element abundances of CPX-II suggest equilibration with carbonatite-like melts that bear close similarities with the carbonatites that enriched the lithosphere in the southern part of the Arabian plate. The similarity of the P-T gradients recorded by the Natash and southern part of Arabian lithospheres, as well as their re-fertilisation by similar, carbonatite-like agents, is consistent with the presence of a mantle plume at the base of the lithosphere after accretion of the Arabian-Nubian Shield in Late Precambrian. The plume material was fossilized due to secular cooling and became part of the lithospheric mantle before the eruption of the Natash volcanic in Late Cretaceous
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